By Lionel Fry
Atopic eczema is the most typical and protracted dermatological situation noticeable ordinarily perform. during the last few years, advances were made within the genetics of atopy more often than not, more moderen remedies were brought for topical use, and new techniques advised within the etiology. hence, a brand new textual content on atopic eczema is either well timed and worthy. Written through one of many world's such a lot distinct dermatologists, An Atlas of Atopic Eczema presents complete insurance of this epidermis affliction, together with new info on calcineurin inhibitors and their healing concepts. broadly illustrated in colour, the atlas explores subject matters akin to genetics, etiology, pathogenesis, analysis, scientific positive factors, differential analysis, relationships to different kinds of eczema, and remedy. the writer lifts the veil of misunderstanding and is helping physicians remain on most sensible of the problem the elevated prevalence of eczemas current.
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Extra resources for An Atlas of Atopic Eczema (Encyclopedia of Visual Medicine Series)
Eczema at these sites is thought to be a manifestation of atopic eczema because it is commonly seen with classical lesions of atopic eczema. When it occurs solely at these sites, there is a strong personal or family history of atopy. LipsÐcheilitis Dry lips are very common in atopic individuals and if severe, the lips peel and become fissured. If this becomes chronic, the associated inflammation may result in thickening of the lips. The skin around the vermillion border of the lip may also be affected and this presents as redness and scaling (Figure 64).
One possibility is that receptors in the endothelium of cutaneous vessels have developed symmetrically, as has the human body. In eczema and psoriasis, the rash is dependent on inflammatory cells coming into the skin via specialized receptors. Altered pigmentation Inflammation in the skin may either stimulate or suppress melanocyte function. Thus, the skin at the sites of the eczema may either become darker (Figures 59 and 60) or paler (Figures 61 and 62). The pigmentary changes often become more apparent CLINICAL FEATURES 25 Figure 17 Subacute eczema with crusts and some erosions Figure 18 Loss of surface of the skin with a weeping surface in acute eczema after the eczema has cleared.
Urticaria and migraine Although migraine and urticaria are not considered to be part of the atopic state, there does appear to be an increased incidence in so-called atopic individuals. Migraine and urticaria may have specific external triggers, as do the classical atopic disorders. However, the exact pathogenetic mechanisms have not been elucidated for migraine, urticaria and atopic disorders, and thus there is speculation whether there could be a common predisposing factor to these diseases. Atopic keratoconjunctivitis This is distinct from the ‘allergic’ conjunctivitis that occurs with rhinitis.
An Atlas of Atopic Eczema (Encyclopedia of Visual Medicine Series) by Lionel Fry